Description
Anastrozole is a well-known aromatase inhibitor (AI), mostly used in medicine but also applied in bodybuilding contexts.
🔹 General Information
- Substance name: Anastrozole
- Drug class: Aromatase Inhibitor (AI)
- Brand names: Most commonly Arimidex
- Form: Oral tablets (typically 1 mg)
🔹 Medical Use
- Prescribed to postmenopausal women with hormone-receptor-positive breast cancer
- Works by blocking the aromatase enzyme, which converts androgens (testosterone) into estrogens → lowers estrogen levels in the body
- Helps slow or stop tumor growth in estrogen-dependent cancers
🔹 Sports / Bodybuilding Context
- Used off-label by athletes and bodybuilders during or after anabolic steroid cycles
- Purpose: Control estrogenic side effects (gynecomastia, water retention, fat gain) caused by aromatization of steroids like testosterone
- Also helps athletes maintain a drier, leaner look during cutting cycles
🔹 Dosage (general ranges)
- Medical use: 1 mg daily
- Sports use (off-label): Typically 0.25–0.5 mg every other day, adjusted based on cycle compounds and estrogen response
(Note: too much suppression can lead to joint pain, mood issues, and negative impact on cholesterol)
🔹 Side Effects
- Joint pain, stiffness
- Hot flashes, fatigue
- Lower bone mineral density (with long-term use)
- Negative impact on cholesterol profile if abused
- Too much estrogen suppression can cause low libido and poor mood
✅ In short: Anastrozole is an aromatase inhibitor that lowers estrogen, mainly used for breast cancer treatment but also applied in bodybuilding to control estrogenic side effects of AAS.
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