Anaridex (Anastrozole, Arimidex)

Description

Arimidex is an anti-estrogen aromatase inhibitor (AI) drug which was originally formulated as a medication for breast cancer in post-menopausal women and is still used for that purpose today.
Arimidex (Anastrozole) PCTArimidex (Anastrozole) PCT

The generic name of Arimidex is Anastrozole and while there are several other brand names used around the world, Arimidex is by far the most common and widely used and known.

It’s the Arimidex brand that is very popular among steroid users to address the estrogenic side effects we experience with the use of many anabolic steroids. For this purpose, Arimidex is almost always recommended for use in a steroid cycle.

What is Arimidex (Anastrozole)?

By blocking the aromatase enzyme, Arimidex directly lowers the levels of estrogen circulating in the body. This is critical for treating breast cancer because of estrogen’s function on cancer cells, but also serves a great purpose for steroid users as estrogen is the enemy of steroid use and is responsible for many of the severe side effects we all want to avoid.
Anastrozole (Arimidex) StructureAnastrozole (Arimidex) Structure

As one of the best aromatase inhibitors, Arimidex is considered the most effective choice for combating the estrogenic side effects of aromatizing steroid use like gynecomastia, water retention and the associated high blood pressure that can come with excess water retention.

While not all steroids aromatize, the most common anabolic steroids that you’re likely to be using, like all forms of Testosterone, Nandrolone, Dianabol and others come with strong estrogenic effects as a result of aromatization.

Therefore the use Arimidex in post cycle therapy is going to be a high priority for the majority of steroid users, whether you’re a beginner or advanced user or somewhere in between.
Arimidex for Gynecomastia and Estrogen Control On-Cycle

Using Arimidex during a cycle is almost universal among steroid users as an estrogenic related side effects protection strategy.

The main estrogenic side effects of aromatizing steroids are water retention (and possible high blood pressure), and gynecomastia. Arimidex is considered as extremely effective at inhibiting the aromatase enzyme which brings about these side effects in steroid users.

Because Arimidex stops the rise of estrogen levels at the most basic level, rather than selectively blocking some receptors like SERMs (Clomid, Nolvadex) do, most bodybuilders prefer Arimidex for its more powerful estrogen controlling ability and many no longer use SERMs, while some steroid users will use a combination of both SERMs and AIs (Arimidex and Letrozole).

As a bodybuilder using steroids, the two side effects you always want to avoid are water retention and gynecomastia (gyno). These are both caused by rising levels of estrogen as your natural testosterone is suppressed while taking steroids.
Arimidex for Gyno

The more powerfully aromatizing the steroid or steroids you’re taking are, the more severe your estrogen related side effects will be when it comes to gyno and water retention. The initial symptoms of gyno include tenderness and swelling of the breast tissue, and this is an initial sign that gyno is taking hold as a result of your steroid cycle.

While advanced steroid users will know how to prevent this occurring through the proper use of Arimidex and other drugs, new steroid users can take some time to balance the right dosage of steroids with that of Arimidex.

It’s critically important that the symptoms of gyno are not left to progress to a stage where they are not reversible through any means besides invasive surgery.

Arimidex as an aromatase inhibitor makes it possible to avoid getting yourself into that situation, and therefore should be considered as just as an important part of your steroid cycle as the steroids themselves are.

Arimidex for Water Retention

Water retention is the other area where we need to be focused on estrogen control during a steroid cycle. Bloating caused by water retention is not only unsightly for your physique, but can give you a false sense of achievement with your gains.

This quickly turns to disappointment once you realize the weight gained was mostly water rather than muscle. But even more serious is the issue of high blood pressure that can result from excess water retention – increasing the risk of stroke or heart attack.

It goes without saying then that controlling water retention as much as possible is vital not only for your results, but your health too. Arimidex with its anti-estrogen functionality provides an important tool for steroid using bodybuilders to prevent or at least greatly minimize water retention during a steroid cycle.

Arimidex for Post Cycle Therapy (PCT)

Arimidex has the ability to stimulate natural testosterone production in men and this can make it useful during post cycle therapy where the goal is to build up natural testosterone levels again after they’ve been strongly suppressed during a cycle.

Keep in mind that for most guys, Arimidex alone will not be strong enough as a testosterone stimulator to use alone in post cycle therapy, and some choose not to use it at all.

The main reason for not including Arimidex in post cycle therapy is because of its very powerful estrogen lowering effect which in some cases can cause levels of the hormone to drop too low to support proper body functioning.

While estrogen is not a prime hormone for males, some is still required and the use of Arimidex during post cycle therapy can inhibit this necessary function and therefore not provide the beneficial effects you really need during post cycle therapy.

This can come as some surprise to new steroid users who assume AIs, with their exceptionally powerful estrogen reduction ability, must be the best option for post cycle therapy as well but most users will choose to go the route of SERMs like Nolvadex or Clomid.

You can go ahead and combine these with hCG for maximum effect during post cycle therapy, where your core goals are stimulating natural testosterone function again and avoiding the horrendous symptoms of low testosterone, plus ensuring all or most of the gains made during your steroid cycle are maintained.

When it comes to these post cycle therapy goals, Arimidex is rarely the most ideal drug to include in the cycle despite its excellent and important usage during your steroid cycle itself.
Arimidex Dosage
Anastrozole Dosage During Anabolic Steroid Use

Arimidex is a highly effective aromatase inhibitor at low doses for estrogen control when using steroids that aromatize. Many guys will find that 0.5mg every two days is enough to mitigate all side effects.

Others will need to increase to 1mg every two days. While some people will take as much as 1mg of Arimidex everyday during a cycle this is usually unnecessary and it’s also advised to test your individual response to the drug by starting out at the lower dose.
Female Arimidex Dosage

Because it has such strong estrogen suppressive effects, Arimidex is mostly only given to post-menopausal women as a breast cancer treatment to slow the growth of some types of tumors and where the cancer is still progressing after the use of SERM drugs. The most common dosage is 1mg daily.

Many women will be required to take Arimidex for up to five years to help control the growth of cancerous tumors. This long term administration of Arimidex comes with increased risk of side effects that we rarely or never see with the short term use that steroid users undertake with this drug.

As Arimidex is not prescribed medically for the majority of women with breast cancer who have not yet reached menopause, female steroid users also should not use this drug for any purpose.
Arimidex Dosage for PCT and Increased Endogenous Testosterone Secretion

As mentioned already, Arimidex is not a prime choice for post cycle therapy purposes for the majority of steroid users.

While it has some function for helping stimulate the production of testosterone, its highly suppressive effects on estrogen can result in a less than ideal effect on testosterone production and a result that is not as effective as using SERMs like Nolvadex and Clomid, which are more commonly used for PCT purposes, in conjunction with hCG (Human chorionic gonadotropin).

While everyone reacts differently to different drugs, and your post cycle therapy will also depend on the type of steroid cycle you were on, some may wish to include Arimidex and in these cases a dosage of 0.5mg to 1mg daily during the post cycle therapy cycle is sufficient.

Arimidex vs Nolvadex for PCT

More and more bodybuilders are turning to AIs like Arimidex to meet their needs for a powerful and effective anti-estrogen while using steroids because AIs actually block the function of estrogen, while SERMs like Nolvadex are very selective in how and where they can stop the functioning of estrogen. But many of us are still using Nolvadex and other SERM’s, often in conjunction with AIs.

How does Nolvadex compare with Arimidex and should you still be using a SERM at all? It’s not so black and white, and ultimately it comes down to how your body reacts to the drugs and the strength of your steroid cycle and the associated side effects.

A big advantage that Nolvadex and other SERMs have over Arimidex and AIs is that while Arimidex is likely to have a negative impact on your cholesterol by lowering HDL cholesterol – the good cholesterol type and this is amplified further when it’s used with most anabolic steroids, Nolvadex does not come with this concern.

In fact Nolvadex can potentially be good for cholesterol; quite the opposite to Arimidex in this regard. This is a big reason, especially for those concerned with cholesterol health, that people will choose to use SERMs over an AI like Arimidex particularly for more mild steroid cycles where an AI might not be needed anyway.

There’s another huge benefit to Nolvadex though: it is very effective during post cycle therapy to stimulate the natural production of testosterone following suppression during a steroid cycle.

Arimidex and SERMs in general simply don’t excel at this function because although it has some testosterone stimulating effects, the way Arimidex suppresses estrogen levels so much that there is not enough for normal functioning makes testosterone stimulation quite weak and not often enough to provide the much needed benefits during post cycle therapy.

Therefore Arimidex is rarely recommended for use during post cycle therapy and instead is considered to be a drug that is mostly used during a steroid cycle which is where it’s performance and results does outshine that of Nolvadex.

That’s not to say that bodybuilders don’t use Arimidex during post cycle therapy: many do but only in conjunction with other drugs so that every possible angle is covered to aid in total recovery from a powerful steroid cycle.

For people foregoing Arimidex altogether during post cycle therapy, a combination of Clomid, Nolvadex and hCG are often used instead.

The ultimate goal of post cycle therapy is to stimulate testosterone not only for normal functioning as a male, but also to retain your muscle gains and control body fat – both of which will suffer when testosterone levels are lower than normal.